What makes Mr. Brightside by The Killers notable?

'Mr. Brightside' became a defining anthem of the early 2000s, reaching No. 10 on the UK Singles Chart and later being certified multi-platinum. Its popularity spurred a resurgence in interest for indie rock and has been widely covered and referenced in popular culture, solidifying its status as a modern classic. Released on September 29, 2003, 'Mr. Brightside' was The Killers' debut single, marking the band's emergence into the alternative rock scene. Following their formation in Las Vegas and after recording their first EP, this track propelled them to international fame, establishing their distinctive sound.